Induce Biologics is proud to introduce its revolutionary Induce Oi-9™ bioimplant, a next-generation bone regenerative technology engineered to transform the landscape of oral and maxillofacial reconstruction. The discovery of bone morphogenetic protein (BMP) by Dr. Marshall Urist (Science, 1965) marked a turning point in regenerative medicine. By the 1980s, BMP was recognized for its powerful ability to induce bone formation. While recombinant BMPs have been commercialized and widely used as alternatives to autogenous bone grafting, their clinical use has been limited by side effects such as cost, excessive postoperative swelling, neurological complications and heterotopic bone formation. Developed through Induce Biologics’ proprietary Natural Matrix Protein (NMP) process, this human allograft bioimplant harnesses the body’s natural regenerative growth factors – including BMP-2, BMP-7, TGF-â1, VEGF and PDGF – by making them bioavailable in their native matrix form. The result is a bioimplant that provides robust osteoinductive potential without the adverse effects commonly associated with recombinant BMPs. Induce Oi-9™ offers a more effective alternative without the side effects. With over 25,000 patients treated to date, the NMP® technology is clinically proven and has been successfully used in a wide range of applications, including complex ridge augmentation procedures. This presentation will explore the scientific rationale behind the Induce Oi-9™ technology, its development and its demonstrated success across challenging clinical scenarios, setting a new standard in bone grafting.
Learning Objectives:
At the conclusion of this presentation, participants should be able to:
Explain the evolution of osteoinductive bone technologies.
Identify the challenges of grafting using current BMP technologies.
Comprehend the contribution of non-collagenous proteins (NCPs) in bone healing.
Understand the description of the NMP technology that provides the foundation for the Induce Oi-9TM bioimplant.
Understand how Induce Oi-9TM bioimplants can be used to enhance osseous reconstruction in your practice.